LZESH-Study (long-term effects of serotonergic hallucinogens)

LZESH Study (Langzeiteffekte von Serotonergen Halluzinogenen, long-term effects of serotonergic hallucinogens)

Recently, the scientific interest in the effects of serotonergic hallucinogens (`psychedelics´) on humans has resumed. One of the specific characteristics of those substances is the ability to facilitate psychological effects that outlast the acute effects in the body. These characteristics have first been described in the 1950s, and have recently been re-evaluated in the context of the use of psychedelics in psychotherapy. In the present study we interview participants who have gained experiences with psychedelics.  in order to assess subacute and long-term effects on the perception of self, others and the environment. On the other hand, potential risks and side effects will also be investigated. By this means we want to contribute to evaluate the safety profile of those substances. The study is divided into two sections:

In the cross-sectional part, we will assess neuropsychological functioning, psychopathology and aspects of positive psychology of users of psychedelics compared to non-users.

In the follow-up part oft he study, participants experienced with psychedelics from the first part will be re-evaluated after 2.5 years with regard to neuropsychology, psychopathology and potential positive outcomes.