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LZESH-Study (Long-term effects of serotonergic hallucinogens)

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The effects of serotonergic hallucinogens ("psychedelics") such as lysergic acid diethylamide (LSD), psilocybin, dimethyltryptamine (DMT), Ayahuasca or mescaline on humans have been intensively investigated in recent years again. One of the special properties of these substances is their ability to develop mental effects that go beyond the acute main effects after ingestion. These properties have been known since the 1960s and have been subject of scientific interest for several years now and are also increasingly investigated in view of their possible therapeutic potential as adjuncts to psychotherapy.

In our study, we are interviewing people who have experiences with psychedelic substances. Our goal is to determine which medium- and long-term effects have occurred and how they are subjectively evaluated by the participants themselves. On the one hand, this possibly includes effects on the perception and experience of self, others and the environment. On the other hand, potential risks and side effects that could occur with continued regular use of psychedelics will also be investigated. In this way, we would like to find out more about the therapeutic potential of psychedelics and contribute to research regarding the safety profile of these substances.

Further information


Principal Investigator
Dr. Tomislav Majić
Dr. Dipl.-Psych. Thomas Riemer

Doctoral candidates and co-workers
Simon Reiche
Tim Hirschfeld
Lukas Basedow
Anna Gröticke
Dipl.-Psych. Marie Traub
Dipl.-Psych. Linda Ortlieb

Master students
Rico Haas
Lara Sedlaczek
Nicklas Hafiz