Research division Psychotic disorders
The division of psychotic disorders is interested in the neurobiological, functional and genetic correlates of psychotic disorders and prodromal states as well as in the investigation of pharmacological and psychotherapeutic treatment options. Another field of interest is to explore the subjective, interpersonal and institutional aspects in the understanding and treatment of patients diagnosed with psychoses.
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Current projects comprise:
- Early recognition and treatment of psychotic disorders: The centre for early recognition and treatment for psychotic disorders (FeTZ) focuses the neurobiological underpinnings of the early course of psychotic illness using brain imaging, electrophysiological and neuropsychological methods. Detailed information about the activities of the FeTZ is provided here: www.charite.de/fetz.
- The investigation of the neurobiological, functional and genetic correlates of social cognitive and interpersonal processes in patients with psychoses and their relatives, and of the efficacy of psychotherapeutic treatment approaches targeting mentalising capacity and social interaction (research group "Empathy and interpersonal processes")
- The investigation of the efficacy of psychotherapeutic treatments for patients with psychoses: An RCT regarding the effects of manualized, Modified Psychodynamic Psychotherapy for Schizophrenia (MPP-S study) is currently conducted by group "Empathy and interpersonal processes" in cooperation with Prof. Dr. med. Dorothea von Haebler, International Psychoanalytic University Berlin. Evidence for the efficacy of art therapy in acute psychotic episodes was supported by a pilot RCT (KUSS study, in cooperation with Prof. Dr. Karin Dannecker, Berlin Weissensee School of Art).
- The basic-scientific investigation of predictors and endophenotypes in schizophrenia using brain imaging, electrophysiological and neuropsychological methods. Molecular genetic analyses focusing the effects and side-effects of antipsychotic drugs aim at the development of individualised pharmacological treatment options entailing lower risks for patients (Prof. Dr. med. Florian Schlagenhauf, AG Lernen und Kognition; PD Dr. med. Andres Neuhaus, Cognitive Neurophysiology Lab; Prof. Dr. med. Daniel Müller, Prof. Dr. med. Imke Puls, research group Empathie und interpersonelle Prozesse).
- In the social psychiatric field, modern treatment approaches like ACT and hometreatment are currently evaluated with respect to patient-centered outcomes and efficiency (research group "Empathy and interpersonal processes").
- Patients' subjective experience of coercive interventions in psychiatry and strategies their reduction are currently investigated in a government-financed, joint research project (ZVP-study) with the federal association Bundesarbeitsgemeinschaft Gemeindepsychiatrischer Verbünde e. V. (AG Empathie und interpersonelle Prozesse, AG Sozialpsychiatrie und Versorgungsforschung).