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The Division of Affective Disorders comprises seven research groups which investigate the pathogenesis as well as treatment and prevention approaches in affective disorders. The Mood Disorders Research Group studies major depressive disorders and bipolar disorders with a special focus on treatment-resistant courses which frequently occur as challenging in clinical care. The Chronic Depression Research Group has its major focus on chronic courses which often develop after emotional maltreatment early in life. Innovative psychotherapeutic approaches, such as CBASP, are a main field of interest of the group. The Anxiety Disorders Research Group investigates the development of pathological anxiety as well as approaches to optimize the treatment of anxiety and phobias. The Research Group Geriatric Psychiatry and Psychotherapy focuses on the investigation of psychiatric disorders and their treatment in elderly patients. The Research Group on Psychotraumatology focuses on the neurobiological mechanisms in the development of trauma-related mental ill-health. The Research Group on Sports Psychiatry and Psychotherapy studies the effect of different modes of exercise on mental ill-health. The Interdisciplinary Research Group on Neurourbanism investigates in a joint approach between neuroscientists and urban researchers the effect of city living and upbringing on the mental health of urban dwellers.